87639-40-5

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 4-phenyl-3-butynyl ester
• CAS NO: 87639-40-5
• Molecular Formula: C11H9F3O3S
• Molecular Weight: 278.252
• Mol File: 87639-40-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 4-phenyl-3-butynyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 4-phenyl-3-butynyl ester(87639-40-5)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 4-phenyl-3-butynyl ester(87639-40-5)

Safety Data

• Hazardous Substances Data: 87639-40-5(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 10229-11-5 4-phenyl-but-3-yn-1-ol 

Downstream Products

• 3481-02-5 cyclopropyl phenyl ketone 
• 906752-55-4 1-(4-phenyl-but-3-ynyl)-2-vinyl-pyridinium triflate 
• 1229283-35-5 1-(isoquinolin-1-ylethynyl)-2-(4-phenylbut-3-ynyl)isoquinolinium trifluoromethanesulfonate 
• 1374023-94-5 diethyl 2-(allylamino)-2-(4-phenylbut-3-ynyl)malonate 
• 1374024-19-7 diethyl 2-amino-2-(4-phenylbut-3-ynyl)malonate 
• 1265135-35-0 2-(1-hexynyl)-1-(4-phenyl-3-butynyl)pyridinium trifluoromethanesulfonate 

Relevant articles and documents

Regioselective Formation of Substituted Indoles: Formal Synthesis of Lysergic Acid

A Diels–Alder reaction-based strategy for the synthesis of indoles and related heterocycles is reported. An intramolecular cycloaddition of alkyne-tethered 3-aminopyrones gives 4-substituted indolines in good yield and with complete regioselectivity. Additional substitution is readily tolerated in the transformation, allowing synthesis of complex and non-canonical substitution patterns. Oxidative conditions give the corresponding indoles. The strategy also allows the synthesis of carbazoles. The method was showcased in a formal synthesis of lysergic acid.

The combination of relay and cooperative catalysis with a gold/palladium/brnsted acid ternary system for the cascade hydroamination/ allylic alkylation reaction

The combination of relay and cooperative catalysis with a gold/palladium/Brnsted acid ternary system renders a cascade hydroamination/allylic alkylation reaction to provide an unprecedented entry to pyrrolidine derivatives in high yields. Copyright

Highly modular assembly of cationic helical scaffolds: rapid synthesis of diverse helquats via differential quaternization

A protocol for rapid and highly modular assembly of a diverse set of helquats is described. From a common bis-isoquinoline precursor, two successive distinct pyridine-type nitrogen quaternizations followed by rhodium-catalyzed [2+2+2] cycloaddition afford non-symmetric [7]helquats. This route allows for straightforward molecular editing of cationic helical skeletons as exemplified by the synthesis of 15 different [5]-, [6]-, and [7]helquats.