876708-01-9 Usage
Description
2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) is a chemical compound that features a pyrimidine ring and an azide functional group attached to a β-D-arabinofuranosyl sugar molecule. This unique structure positions it for potential applications in various fields, including medicinal chemistry, drug development, and the study of nucleic acids and nucleoside analogs. The presence of the pyrimidine ring suggests possible interactions with enzymes and biological pathways related to nucleic acid metabolism and DNA replication.
Uses
Used in Medicinal Chemistry:
2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs targeting specific biological pathways.
Used in Drug Development:
In the field of drug development, 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) serves as a potential candidate for the creation of novel therapeutic agents. Its azide group and pyrimidine ring may contribute to the compound's ability to modulate biological processes and target specific enzymes or receptors.
Used in Nucleic Acid Research:
2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) is utilized in the study of nucleic acids and nucleoside analogs. Its structure allows researchers to investigate its interactions with enzymes and biological pathways involved in nucleic acid metabolism and DNA replication, potentially leading to advancements in understanding and treating related diseases.
Further research is necessary to fully explore the potential uses and applications of 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) in these and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 876708-01-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,6,7,0 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 876708-01:
(8*8)+(7*7)+(6*6)+(5*7)+(4*0)+(3*8)+(2*0)+(1*1)=209
209 % 10 = 9
So 876708-01-9 is a valid CAS Registry Number.
876708-01-9Relevant articles and documents
Azido nucleosides and nucleotide analogs
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, (2016/06/13)
Disclosed herein are 4′-azido-substituted nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of 4′-azido-substituted nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a 4′-azido-substituted nucleoside, a nucleotide and/or an analog thereof. Examples of viral infections include a respiratory syncytial viral (RSV) and influenza infection.
The design, synthesis, and antiviral activity of 4′-azidocytidine analogues against hepatitis C virus replication: The discovery of 4′-azidoarabinocytidine
Smith, David B.,Kalayanov, Genadiy,Sund, Christian,Winqvist, Anna,Pinho, Pedro,Maltseva, Tatiana,Morisson, Veronique,Leveque, Vincent,Rajyaguru, Sonal,Pogam, Sophie Le,Najera, Isabel,Benkestock, Kurt,Zhou, Xiao-Xiong,Maag, Hans,Cammack, Nick,Martin, Joseph A.,Swallow, Steven,Johansson, Nils Gunnar,Klumpp, Klaus,Smith, Mark
experimental part, p. 219 - 223 (2009/10/01)
4′-Azidocytidine 3 (R1479) has been previously discovered as a potent and selective inhibitor of HCV replication targeting the RNA-dependent RNA polymerase of hepatitis C virus, NS5B. Here we describe the synthesis and biological evaluation of several der
