876756-13-7

Basic information

• Product Name: Carbamic acid, [4-(1-hydroxy-1-methylethyl)-2-thiazolyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [4-(1-hydroxy-1-methylethyl)-2-thiazolyl]-, 1,1-dimethylethyl ester (9CI);tert-Butyl (4-(2-hydroxypropan-2-yl)thiazol-2-yl)carbamate
• CAS NO: 876756-13-7
• Molecular Formula: C11H18N2O3S
• Molecular Weight: 258.34
• Mol File: 876756-13-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.237±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.20±0.70(Predicted)
• CAS DataBase Reference: Carbamic acid, [4-(1-hydroxy-1-methylethyl)-2-thiazolyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [4-(1-hydroxy-1-methylethyl)-2-thiazolyl]-, 1,1-dimethylethyl ester (9CI)(876756-13-7)
• EPA Substance Registry System: Carbamic acid, [4-(1-hydroxy-1-methylethyl)-2-thiazolyl]-, 1,1-dimethylethyl ester (9CI)(876756-13-7)

Safety Data

• Hazardous Substances Data: 876756-13-7(Hazardous Substances Data)

Upstream product

• 762271-84-1 (4-Acetyl-thiazol-2-yl)-carbamic acid tert-butyl ester 
• 75-16-1 methylmagnesium bromide 
• 850429-62-8 methyl 2-[[(tert-butoxy)carbonyl]amino]-1,3-thiazole-4-carboxylate 

Relevant articles and documents

1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS

A compound of formula (I), wherein R, R1, R2, R3, Y, Y1, a, X, and Z are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne Muscular Dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.