87682-27-7Relevant articles and documents
Reactions of (CO)5MnSi(CH3)3 and CO with aldehydes and cyclic ethers. Syntheses of functionalized pentacarbonylmanganese acyls and homologated organic compounds
Brinkman, Kerry C.,Gladysz
, p. 147 - 155 (2008/10/08)
Reactions of (CO)5MnSi(CH3)3 (1) and CO with aldehydes RCHO and cyclic ethers OCH2(CH2)nCH2 (n = 0-2) give manganese acyls (CO)5MnCOCH(R)OSi(CH3)3 and (CO)5MnCOCH2(CH2)nCH 2OSi(CH3)3 (n = 0, 6; n = 1, 9; n = 2, 10) in 26-72% and 54-87% yields, respectively. Experiments conducted in the absence of CO show that these transformations proceed via labile alkyl intermediates (CO)5MnCH(R)OSi(CH3)3 and (CO)5MnCH2(CH2)nCH 2OSi(CH3)3. Reactions of propylene oxide and cyclohexene oxide with 1 and CO give the manganese acyls expected from SN2 ring opening. When the reaction of 1 with aldehydes is conducted in the presence of (CO)5MnH under careful conditions, homologated aldehydes (CH3)3SiOCHRCHO form in 55-78% yields. Reaction of 1 and (CO)5MnH with oxetane gives (CH3)3-SiOCH2CH2CH2CHO (13, 38%) and (CH3)3SiOCHCH2CH2CH2O (14, 59%). Reaction of 9 and 10 with [(CH3CH2)2N]3S+Si(CH 3)3F2- yields γ-butyrolactone (84-95%) and δ-valerolactone (60-85%), respectively. The mechanisms of these transformations, and their utility in organic and organometallic synthesis, are discussed.
