87707-58-2

Basic information

• Product Name: 3-(4-N,N-dimethylaminobenzyl)benzoxazoline-2-thione
• CAS NO: 87707-58-2
• Molecular Weight: 284.382
• Mol File: 87707-58-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-N,N-dimethylaminobenzyl)benzoxazoline-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-N,N-dimethylaminobenzyl)benzoxazoline-2-thione(87707-58-2)
• EPA Substance Registry System: 3-(4-N,N-dimethylaminobenzyl)benzoxazoline-2-thione(87707-58-2)

Safety Data

• Hazardous Substances Data: 87707-58-2(Hazardous Substances Data)

Upstream product

• 1624-49-3 2-(4-dimethylamino-benzylidenamino)-phenol 
• 95-55-6 2-amino-phenol 
• 99074-89-2 2-(N,N-dimethyl-4-aminophenyl)acetaldehyde 
• 75-15-0 carbon disulfide 
• 199791-16-7 2-(4-dimethylaminobenzylideneimino)phenol 

Relevant articles and documents

Synthesis of 3-Substitued Benzoxazoline-2-thiones

Several methods for the preparation of 3-substitued benzoxazoline-2-hiones (1) were examined.Method B via the thiation of 3-substitued benzoxazoline-2-one (5) with phosphorus pentasulfide was found to be applicable to the preparation of most analogs of 1, with a few expections.Method C via the cyclization of 2-(alkylamino)phenol (7) with potassium O-methyldithiocarbonate was suitable for the preparation of analogs with a group sensitive to high temperature of with an aryl- (including aromatic heterocyclic ring) methyl group.In addition, the reaction of benzoxazoline-2-thione (2) with acetals such as 1-ethoxyisochroman, 2-ethoxytetrahydrofuran, and ethoxytetraydropyran, or with Michael acceptors such as 2,3-dihydrofuran and 2H-3,4-dihydropyran, gave 3-substitued benzoxazoline-2-thione (1d-f).