877128-35-3

Basic information

• Product Name: Phosphonic acid, [2-(methoxymethoxy)-5-methylphenyl]-, diethyl ester
• CAS NO: 877128-35-3
• Molecular Formula: C13H21O5P
• Molecular Weight: 288.28
• Mol File: 877128-35-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [2-(methoxymethoxy)-5-methylphenyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [2-(methoxymethoxy)-5-methylphenyl]-, diethyl ester(877128-35-3)
• EPA Substance Registry System: Phosphonic acid, [2-(methoxymethoxy)-5-methylphenyl]-, diethyl ester(877128-35-3)

Safety Data

• Hazardous Substances Data: 877128-35-3(Hazardous Substances Data)

Upstream product

• 25458-49-5 1-(methoxymethoxy)-4-methylbenzene 
• 814-49-3 diethyl chlorophosphate 

Downstream Products

• 105865-37-0 4-Methyl-2-phosphinophenol 
• 408541-33-3 4-methyl-2-phosphinophenyl-methoxymethylether 

Relevant articles and documents

PH-functional o-phosphinophenols - Synthesis via methoxymethylethers and screening tests for Ni-catalyzed ethylene polymerization

Various primary and secondary 2-phosphinoaryl methoxymethylethers were prepared via orthometallation of methyl- and methoxy-substituted aryl methoxymethylethers and subsequent reaction with aminochlorophosphines, followed by alcoholysis and reduction with excess LiAlH4. Incomplete reduction provides 2-methoxymethoxy-substituted cyclotetraphosphines, isolated and characterized by X-ray crystal structure analysis in one case. An example of the facile P-alkylation of primary to secondary representatives is also given. Secondary 2-phosphinophenols, obtained by selective cleavage of the MOM-protection group, and even the primary 2-phosphino-4-methylphenol react with Ni(COD)2 to form ethylene polymerization catalysts. 4-Methoxy groups cause a strong increase of the molecular weights and a bimodal molecular weight distribu tion of the polymerization products; neither effect is observed for tertiary phosphinophenolate/Ni polymerization catalysts.