877314-35-7Relevant articles and documents
Synthesis of thieno[2,3-b]pyridinones acting as cytoprotectants and as inhibitors of [3H]glycine binding to the N-methyl-D-aspartate (NMDA) receptor
Buchstaller, Hans-Peter,Siebert, Carsten D.,Steinmetz, Ralf,Frank, Ina,Berger, Michael L.,Gottschlich, Rudolf,Leibrock, Joachim,Krug, Michael,Steinhilber, Dieter,Noe, Christian R.
, p. 864 - 871 (2007/10/03)
The standard glycine site antagonist of the N-methyl-D-aspartate (NMDA) receptor, 3-phenyl-4-hydroxyquinolin-2(1H)-one (21), was used as a template for bioisostere benzene/thiophene exchange. Phenylacetylation of aminothiophene carboxylic acid methyl este