87736-89-8 Usage
Description
4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester is a novel aromatic diazirine compound characterized as a white solid. It is known for its unique photoaffinity labeling capabilities, which make it a valuable tool in various research and industrial applications.
Uses
Used in Photoaffinity Labeling Applications:
4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester is used as a photoaffinity labeling agent for the identification and characterization of biomolecular targets. Its ability to covalently bind to target molecules upon exposure to light allows for the study of protein-ligand interactions, enzyme mechanisms, and the elucidation of molecular structures.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester serves as a key component in the development of drugs targeting specific proteins or enzymes. Its photoaffinity labeling properties enable researchers to investigate the binding sites and mechanisms of action of potential drug candidates, thereby facilitating the design of more effective and selective medications.
Used in Chemical Synthesis:
4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester is also utilized in chemical synthesis processes, particularly in the preparation of complex organic molecules and the modification of existing compounds. Its reactivity and stability make it a versatile building block for the creation of novel chemical entities with potential applications in various fields.
Used in Materials Science:
In materials science, 4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester is employed in the development of advanced materials with specific properties. Its incorporation into polymers, coatings, and other materials can lead to the creation of new products with improved characteristics, such as enhanced stability, selectivity, or responsiveness to environmental stimuli.
Check Digit Verification of cas no
The CAS Registry Mumber 87736-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,7,3 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87736-89:
(7*8)+(6*7)+(5*7)+(4*3)+(3*6)+(2*8)+(1*9)=188
188 % 10 = 8
So 87736-89-8 is a valid CAS Registry Number.
87736-89-8Relevant articles and documents
Anticancer Pyrroloquinazoline LBL1 Targets Nuclear Lamins
Li, Bingbing X.,Chen, Jingjin,Chao, Bo,David, Larry L.,Xiao, Xiangshu
, p. 1380 - 1387 (2018)
Target identification of bioactive compounds is critical for understanding their mechanism of action. We previously discovered a novel pyrroloquinazoline compound LBL1 with significant anticancer activity. However, its molecular targets remain to be estab
CELL CYCLE PROGRESSION INHIBITOR
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Paragraph 0080, (2019/09/18)
The present invention provides a cell cycle progression inhibitor, a cytostatic agent, and an anticancer agent. The cell cycle progression inhibitor, the cytostatic agent, and the anticancer agent each contains a Hes1 protein-PHB2 protein binding enhancer.
Tri- and tetravalent photoactivable cross-linking agents
Welle, Alexandre,Billard, Francois,Marchand-Brynaert, Jacqueline
, p. 2249 - 2254 (2012/10/08)
A modular synthesis of photoactivable cross-linking agents is described, using an aromatic core, di- or triethyleneglycol spacers and photoaffinity labeling synthons that feature either perfluorophenyl azide or aryl(trifluoromethyl)diazirine motifs. Symmetrical and nonsymmetrical trivalent structures were obtained from phloroglucinol and dopamine, respectively. Symmetrical tetravalent structures resulted from the coupling of two dopamine derivatives with oxalyl chloride. Georg Thieme Verlag Stuttgart New York.
