877384-24-2

Basic information

• Product Name: (1S,2R)-2-Ethoxy-1,2-diphenyl-ethanol
• Synonyms: (1S,2R)-2-Ethoxy-1,2-diphenyl-ethanol
• CAS NO: 877384-24-2
• Molecular Weight: 242.318
• Mol File: 877384-24-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2R)-2-Ethoxy-1,2-diphenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-2-Ethoxy-1,2-diphenyl-ethanol(877384-24-2)
• EPA Substance Registry System: (1S,2R)-2-Ethoxy-1,2-diphenyl-ethanol(877384-24-2)

Safety Data

• Hazardous Substances Data: 877384-24-2(Hazardous Substances Data)

Upstream product

• 574-09-4 2-ethoxy-1,2-diphenyl-ethanone 

Relevant articles and documents

Hydrogenation of α-Keto Ethers: Dynamic Kinetic Resolution with a Heterogeneous Modified Catalyst and a Heterogeneous Base

The first successful example of the asymmetric hydrogenation of substituted α-keto ethers with Cinchona-modified Pt/Al2O3 is reported. In the absence of an additional base, kinetic resolution of the racemic starting material was observed with high diastereoselectivity and ee's up to 98% at conversions of a strong reaction acceleration but racemic product. Immobilization of OH- on solid ion exchangers resulted in the desired dynamic kinetic resolution, and ee's of >80% were obtained at >95% conversion. These effects are rationalized on the basis of a simple kinetic and structural model.