877678-72-3

Basic information

• Product Name: Carbamic acid, [[4-[4-chloro-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]phenyl]-5-[4-( 2-pyridinyl)-1-piperidinyl]-4H-1,2,4-triazol-3-yl]methyl]-, 1,1-dimethylethyl ester
• CAS NO: 877678-72-3
• Molecular Formula: C31H45ClN6O3Si
• Molecular Weight: 613.275
• Mol File: 877678-72-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[4-[4-chloro-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]phenyl]-5-[4-( 2-pyridinyl)-1-piperidinyl]-4H-1,2,4-triazol-3-yl]methyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[4-[4-chloro-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]phenyl]-5-[4-( 2-pyridinyl)-1-piperidinyl]-4H-1,2,4-triazol-3-yl]methyl]-, 1,1-dimethylethyl ester(877678-72-3)
• EPA Substance Registry System: Carbamic acid, [[4-[4-chloro-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]phenyl]-5-[4-( 2-pyridinyl)-1-piperidinyl]-4H-1,2,4-triazol-3-yl]methyl]-, 1,1-dimethylethyl ester(877678-72-3)

Safety Data

• Hazardous Substances Data: 877678-72-3(Hazardous Substances Data)

Upstream product

• 6926-09-6 (tert-butoxycarbonyl)glycine hydrazide 

Downstream Products

• 877678-73-4 tert-butyl {[4-[4-chloro-2-(hydroxymethyl)phenyl]-5-(4-pyridin-2-ylpiperidiri-1-yl)-4H-1,2,4-triazol-3-y I]methyl}carbamate 

Relevant articles and documents

TRIAZOLOBENZODIAZEPINES AND THEIR USE AS VASOPRESSIN ANTAGONISTS

Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein R represents H, C1-6 alkyl, SO2R1, SO2NR1R2, or COR1; R1 and R2 independently represent C1-6alkyl; and Ring A represents a phenyl ring or a pyridinyl ring; may be useful in the treatment of anxiety, cardiovascular disease (including angina, atherosclerosis, hypertension, heart failure, edema, hypernatremia), dysmenorrhoea (primary and secondary), endometriosis, emesis (including motion sickness), intrauterine growth retardation, inflammation (including rheumatoid arthritis), mittlesmerchz, preclampsia, premature ejaculation, premature (preterm) labor and Raynaud's disease.