877681-24-8

Basic information

• Product Name: (2R)-2-hydroxy-2-(3-methylphenyl)propanoic acid methyl ester
• Synonyms: (2R)-2-hydroxy-2-(3-methylphenyl)propanoic acid methyl ester
• CAS NO: 877681-24-8
• Molecular Weight: 194.23
• Mol File: 877681-24-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2R)-2-hydroxy-2-(3-methylphenyl)propanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-hydroxy-2-(3-methylphenyl)propanoic acid methyl ester(877681-24-8)
• EPA Substance Registry System: (2R)-2-hydroxy-2-(3-methylphenyl)propanoic acid methyl ester(877681-24-8)

Safety Data

• Hazardous Substances Data: 877681-24-8(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 877932-06-4 (2R)-2-hydroxy-2-(3-methylphenyl)propanoic acid 
• 136125-68-3 methyl 3-methylphenylglyoxylate 
• 544-97-8 dimethyl zinc(II) 
• 585-74-0 3-Methylacetophenone 
• 1124-20-5 2-(3-methylphenyl)propene 
• 875542-01-1 (2R)-2-(3-methylphenyl)propane-1,2-diol 

Downstream Products

• 875542-02-2 (5R)-5-methyl-5-(3-methylphenyl)oxazolidine-2,4-dione 
• 877681-25-9 (5R)-5-methyl-5-(3-methylphenyl)-N-trityl-oxazolidine-2,4-dione 
• 875542-03-3 (5R)-5-(3-bromomethylphenyl)-5-methyl-N-trityl-oxazolidine-2,4-dione 

Relevant articles and documents

Enantioselective addition of organozinc reagents to carbonyl compounds catalyzed by a camphor derived chiral γ-amino thiol ligand

In this article, the design and synthesis of the chiral camphor derived γ-amino thiol ligand 17 and its application in catalytic enantioselective carbon-carbon forming reactions through the addition of organozinc reagents to carbonyl compounds is described. The catalytic activity and enantioselectivity of ligand 17 is demonstrated in the enantioselective addition of various organozinc reagents to aldehydes and ketoesters, offering the corresponding alcohols in high yields and enantioselectivities. The role of the mercapto group in the highly enantioselective 1,2-addition reaction of organozincs to aldehyde is also discussed.

Asymmetric addition of dimethylzinc to α-ketoesters catalyzed by (-)-MITH

(Chemical Equation Presented) This investigation describes the catalytic asymmetric addition of dimethylzinc to α-ketoesters in the presence of (-)-MITH (5) and triethyl borate as an additive to give the corresponding chiral α-hydroxy esters with good yie

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