877859-95-5

Basic information

• Product Name: Pyrrolo[3,4-c]pyrazole-1,5-dicarboxylic acid, 4,6-dihydro-3-[[[4-(1-pyrrolidinyl)phenyl]acetyl]amino]-, 5-(1,1-dimethylethyl) 1-ethyl ester
• CAS NO: 877859-95-5
• Molecular Formula: C25H33N5O5
• Molecular Weight: 483.568
• Mol File: 877859-95-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyrrolo[3,4-c]pyrazole-1,5-dicarboxylic acid, 4,6-dihydro-3-[[[4-(1-pyrrolidinyl)phenyl]acetyl]amino]-, 5-(1,1-dimethylethyl) 1-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[3,4-c]pyrazole-1,5-dicarboxylic acid, 4,6-dihydro-3-[[[4-(1-pyrrolidinyl)phenyl]acetyl]amino]-, 5-(1,1-dimethylethyl) 1-ethyl ester(877859-95-5)
• EPA Substance Registry System: Pyrrolo[3,4-c]pyrazole-1,5-dicarboxylic acid, 4,6-dihydro-3-[[[4-(1-pyrrolidinyl)phenyl]acetyl]amino]-, 5-(1,1-dimethylethyl) 1-ethyl ester(877859-95-5)

Safety Data

• Hazardous Substances Data: 877859-95-5(Hazardous Substances Data)

Upstream product

• 26586-36-7 2-(4-(pyrrolidin-1-yl)phenyl)acetic acid 
• 398491-59-3 3-amino-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester 
• 398495-65-3 3-amino-4,6-dihydro-pyrrolo[3,4-c]pyrazole-1,5-dicarboxylic acid 5-tert-butyl ester 1-ethyl ester 
• 877859-93-3 4-(pyrrolidin-1-yl)phenylacetic acid chloride 

Relevant articles and documents

3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors

We have recently reported about a new class of Aurora-A inhibitors based on a bicyclic tetrahydropyrrolo[3,4-c]pyrazole scaffold. Here we describe the synthesis and early expansion of CDK2/cyclin A-E inhibitors belonging to the same chemical class. Synthe