877866-86-9Relevant articles and documents
2,5-Disubstituted pyridines: The discovery of a novel series of 5-HT2A ligands
Wilson, Kevin J.,van Niel, Monique B.,Cooper, Laura,Bloomfield, Dawn,O'Connor, Desmond,Fish, L. Rebecca,MacLeod, Angus M.
, p. 2643 - 2648 (2008/02/01)
This report describes the effect of replacing the central basic amine present in many known 5-HT2A ligands with an aromatic residue. We targeted the isomeric phenethylpyridines 2 and 3 and these compounds proved to be excellent leads, possessin