878155-22-7 Usage
Description
8-amino-2-methyl-3,4-dihydroisoquinolin-1(2H)-one is a heterocyclic organic compound with a unique chemical structure, featuring an isoquinolinone core with an amino group at the 8-position and a methyl group at the 2-position. 8-amino-2-methyl-3,4-dihydroisoquinolin-1(2H)-one has potential applications in various fields due to its chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
8-amino-2-methyl-3,4-dihydroisoquinolin-1(2H)-one is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
8-amino-2-methyl-3,4-dihydroisoquinolin-1(2H)-one is used as a building block in the synthesis of complex organic molecules. Its reactivity and functional groups make it a versatile component in the creation of novel chemical entities.
Used in Research and Development:
8-amino-2-methyl-3,4-dihydroisoquinolin-1(2H)-one is utilized in research laboratories for the study of its chemical properties, reactivity, and potential applications. It serves as a valuable tool for understanding the behavior of similar compounds and developing new synthetic methods.
An alternative microwave-assisted synthesis of 8-Amino-3,4-dihydro-2-methyl-1(2H)-isoquinolinone has been examined, which includes two one-pot procedures. The key process involves the microwave-assisted hydrolysis of a nitrile group followed by lactamization under elevated temperatures, providing an efficient and innovative method for the production of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 878155-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,1,5 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 878155-22:
(8*8)+(7*7)+(6*8)+(5*1)+(4*5)+(3*5)+(2*2)+(1*2)=207
207 % 10 = 7
So 878155-22-7 is a valid CAS Registry Number.
878155-22-7Relevant articles and documents
CXCR7 RECEPTOR MODULATORS
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Page/Page column 198, (2014/12/12)
The present invention relates to derivatives of formula (I) Formula (I) wherein (R1)n, R 2a, R 2b, R 3a, R 3b, R 4, L1, L2, X, Y and Ar1 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as CXCR7 receptor modulators.
A microwave-assisted alternative synthesis of 8-amino-2-methyl-3,4- dihydroisoquinolin-1-one
Glossop, Steve C.
, p. 981 - 983 (2008/02/02)
A shorter, alternative synthesis of 8-amino-2-methyl-3,4- dihydroisoquinolin-1-one is described in 32% overall yield, over three steps starting from commercially available 2-methyl-6-nitrobenzonitrile. The synthesis includes two 'one-pot' procedures in wh
