87823-49-2

Basic information

• Product Name: 2,5-Morpholinedione,3-methyl-(9CI)
• Synonyms: 2,5-Morpholinedione,3-methyl-(9CI)
• CAS NO: 87823-49-2
• Molecular Formula: C5H7NO3
• Molecular Weight: 129.11398
• Product Categories: GLYCINESCAFFOLD
• Mol File: 87823-49-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Morpholinedione,3-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Morpholinedione,3-methyl-(9CI)(87823-49-2)
• EPA Substance Registry System: 2,5-Morpholinedione,3-methyl-(9CI)(87823-49-2)

Safety Data

• Hazardous Substances Data: 87823-49-2(Hazardous Substances Data)

Usage

Heterocyclic compound

A compound containing a ring structure with at least one non-carbon atom, in this case, nitrogen, which contributes to its unique chemical properties and reactivity.

Morpholine ring

A six-membered heterocyclic ring with two oxygen atoms and four carbon atoms, which imparts specific characteristics to the compound, such as its ability to act as a building block in organic synthesis.

Lactone group

A cyclic ester functional group (-CO-O-) present in the compound, which is responsible for its wide range of biological activities and potential applications in drug development.

Building block in organic synthesis

The compound is used as a starting material or intermediate in the synthesis of more complex organic molecules, particularly in the production of pharmaceuticals, agrochemicals, and specialty chemicals.

Potential applications in drug development

Due to its unique structure and reactivity, the compound can be used to develop new drugs and chemical products with various therapeutic and industrial applications.

Wide range of biological activities

The compound exhibits various biological activities, making it a valuable raw material for the synthesis of derivatives with different properties and potential applications in medicine and other fields.

Synthesis of various derivatives

The compound can be modified and functionalized to create a diverse range of derivatives with altered properties, further expanding its potential applications in various industries.

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Relevant articles and documents

CROSSLINKED POLY-DEPSIPEPTIDE COPOLYMERS AND METHODS OF MAKING THEREOF

Aspects of the present disclosure include methods for preparing crosslinked polydepsipeptide copolymers by stereolithography (e.g., 3-D printing). In practicing methods according to certain embodiments, a crosslinkable copolymer containing a depsipeptide

Biodegradable photocrosslinkable poly(depsipeptide-co-caprolactone) for tissue engineering: Synthesis, characterization, and in vitro evaluation

Stereolithography has become increasingly popular in scaffold fabrication due to automation and well-controlled geometry complexity, and consequently, there is a great need for new suitable biodegradable photocrosslinkable polymers. In this study, a new type of photocrosslinkable poly(ester amide) was synthesized based on e-caprolactone and L-alaninederived depsipeptide and was applied to fabrication of threedimensional (3D) scaffolds by stereolithography. 1H nuclear magnetic resonance and Fourier transform infra-red analysis confirmed the formation of new bonds during the polymer synthesis. Incorporation of depsipeptide increased the glass transition temperature and hydrophilicity of the polymer and accelerated hydrolytic degradation compared with the poly(ecaprolactone) homopolymer. The compressive strength of the 3D scaffolds increased with the increasing depsipeptide content. This work demonstrated that incorporation of depsipeptide into photocrosslinkable polyesters resulted in excellent cytocompatibility and tunable degradation rates and mechanical properties and thus expanded the repertoire of biomaterials suitable for 3D photofabrication of high-resolution tissue engineering scaffolds.

Process for the preparation of 3-, 6-substituted 2,5-morpholinediones

A process for the preparation of 3- and/or 6-substituted 2,5-morpholinediones is disclosed. Such morpholinediones are useful as precursors for the preparation of depsipeptide polymers and copolymers.