87831-90-1Relevant articles and documents
The 2-Thiosulfatoethyl Group as Solubilizing Protective Group in Enzymatic Peptide Synthesis
Kuhl, P.,Walpuski, J.,Jakubke, H.-D.
, p. 465 - 466 (2007/10/02)
Amino acid (2-thiosulfatoethyl esters) 4 can be prepared from amino acid (2-chloroethyl esters) by nucleophilic exchange of halogen for thiosulfate.Coupling of the esters 4 with Z-protected amino acids gives the water-soluble Z-dipeptide esters 5 which re