87834-69-3

Basic information

• Product Name: 17β-benzyloxy-D-13β-ethyl-3-methoxy-estra-1,3,5(10),9(11)-tetraene
• Synonyms: 17β-benzyloxy-D-13β-ethyl-3-methoxy-estra-1,3,5(10),9(11)-tetraene
• CAS NO: 87834-69-3
• Molecular Weight: 388.55
• Mol File: 87834-69-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 17β-benzyloxy-D-13β-ethyl-3-methoxy-estra-1,3,5(10),9(11)-tetraene(CAS DataBase Reference)
• NIST Chemistry Reference: 17β-benzyloxy-D-13β-ethyl-3-methoxy-estra-1,3,5(10),9(11)-tetraene(87834-69-3)
• EPA Substance Registry System: 17β-benzyloxy-D-13β-ethyl-3-methoxy-estra-1,3,5(10),9(11)-tetraene(87834-69-3)

Safety Data

• Hazardous Substances Data: 87834-69-3(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 56376-31-9 Acetic acid (8S,13S,14S,17S)-13-ethyl-3-methoxy-7,8,12,13,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl ester 
• 7443-72-3 18-methyl-3-methoxy-1,3,5(10),8-estratetraen-17β-ol 
• 19882-76-9 (+)-13β-ethyl-3-methoxygona-1,3,5(10),9(11)-tetraene-17β-ol 

Downstream Products

• 87834-70-6 17β-benzyloxy-D-13β-ethyl-11α-hydroxy-3-methoxy-estra-1,3,5(10)-triene 
• 54024-17-8 13β-ethyl-11-methylenegon-4-en-3,17-dione 

Relevant articles and documents

Design of the synthesis of steroidal 1,3,5(10),9(11)-tetraenes via isomerization of 1,3,5(10),8-isomers - Effect of the solvent system

p-Toluenesulphonic acid catalytic isomerization of 1,3,5(10),8-tetraene steroids in benzene or toluene with the presence of acetic acid is established as a simple high-yield (85 ~ 89%) procedure to the synthesis of the corresponding 9(11)-isomers. The solvation effect is discussed for the design of the new reaction media.

Synthesis of 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17α-pregn-4- en-20-yn-3-one (3-oxo desogestrel)

A synthesis of the steroid hormone, 3-keto-desogestrel (1), with the total yield of 10% starting from d-13β-ethyl-3-methoxy-gona-1,3,5(10),8- tetraen-18β-ol (3) is described.