878541-85-6

Basic information

• Product Name: Pyrrolidine, 2-[(4-bromophenyl)methyl]-2-(cyclopropylcarbonyl)-1-[(3,5-dichlorophen yl)acetyl]-
• CAS NO: 878541-85-6
• Molecular Formula: C23H22BrCl2NO2
• Molecular Weight: 495.243
• Mol File: 878541-85-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyrrolidine, 2-[(4-bromophenyl)methyl]-2-(cyclopropylcarbonyl)-1-[(3,5-dichlorophen yl)acetyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 2-[(4-bromophenyl)methyl]-2-(cyclopropylcarbonyl)-1-[(3,5-dichlorophen yl)acetyl]-(878541-85-6)
• EPA Substance Registry System: Pyrrolidine, 2-[(4-bromophenyl)methyl]-2-(cyclopropylcarbonyl)-1-[(3,5-dichlorophen yl)acetyl]-(878541-85-6)

Safety Data

• Hazardous Substances Data: 878541-85-6(Hazardous Substances Data)

Upstream product

• 878541-79-8 tert-butyl 2-(4-bromobenzyl)-2-(cyclopropylcarbonyl)pyrrolidine-1-carboxylate 
• 878541-76-5 tert-butyl 2-(4-bromobenzyl)-2-{[methoxy(methyl)amino]carbonyl}pyrrolidine-1-carboxylate 
• 336817-32-4 1-tert-butyl 2-methyl 2-(4-bromobenzyl)pyrrolidine-1,2-dicarboxylate 
• 878541-82-3 [2-(4-bromobenzyl)pyrrolidin-2-yl](cyclopropyl)methanone 
• 51719-65-4 2-(3,5-dichlorophenyl)acetic acid 
• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Relevant articles and documents

Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold

A new class of lymphocyte function-associated antigen-1 (LFA-1) antagonists is described. Elaboration of the 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold resulted in the synthesis of potent inhibitors of the LFA-1/ICAM-1 interaction. Along with the in vi