879015-12-0Relevant articles and documents
Base-base interactions in the minor groove of double-stranded DNA
Wu, Tongfei,Nauwelaerts, Koen,Van Aerschot, Arthur,Froeyen, Matheus,Lescrinier, Eveline,Herdewijn, Piet
, p. 5423 - 5431 (2007/10/03)
A method has been developed for the synthesis of bisheaded nucleosides with thymine and adenine base moieties. We have demonstrated that, when incorporated in oligonucleotides, extrahelical A-T base interactions are possible when the bisheaded nucleosides