87973-85-1Relevant articles and documents
Synthesis of Novel MPTP Analogs as Potential Monoamine Oxidase B (MAO-B) Inhibitors
Kalgutkar, Amit S.,Castagnoli, Neal
, p. 4165 - 4174 (2007/10/02)
The nigrostratial toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is an excellent substrate and a weak inactivator of the flavoenzyme monoamine oxidase B (MAO-B).In an attempt to develop novel mechanism-based inactivators of MAO-B, we have synth