879904-82-2 Usage
Description
1-Boc-2-(hydroxydimethylsilyl)pyrrole, 97% is a chemical compound that features a pyrrole ring with a Boc protecting group at the 1-position and a hydroxydimethylsilyl group at the 2-position. 1-Boc-2-(hydroxydimethylsilyl)pyrrole, 97% is characterized by its purity of 97%, indicating a high level of quality and consistency in its composition.
Uses
1-Boc-2-(hydroxydimethylsilyl)pyrrole, 97% is used as a substrate in various chemical reactions for the synthesis of different products.
Used in Organic Synthesis:
1-Boc-2-(hydroxydimethylsilyl)pyrrole, 97% is used as a substrate for the preparation of cross-coupling products by reacting with various aryl iodides. This application is valuable for the creation of new organic compounds with potential applications in various fields, such as pharmaceuticals, materials science, and agrochemicals.
Used in the Synthesis of Alkoxyhydrosiloxanes:
1-Boc-2-(hydroxydimethylsilyl)pyrrole, 97% is also used as a substrate in the synthesis of alkoxyhydrosiloxanes by reacting with alkoxyhydrosilanes. This process is important for the development of new siloxane-based materials with unique properties, such as thermal stability, low surface energy, and biocompatibility, which can be utilized in industries like coatings, adhesives, and sealants.
Check Digit Verification of cas no
The CAS Registry Mumber 879904-82-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,9,9,0 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 879904-82:
(8*8)+(7*7)+(6*9)+(5*9)+(4*0)+(3*4)+(2*8)+(1*2)=242
242 % 10 = 2
So 879904-82-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO3Si/c1-11(2,3)15-10(13)12-8-6-7-9(12)16(4,5)14/h6-8,14H,1-5H3
879904-82-2Relevant articles and documents
Palladium-catalyzed cross-coupling of five-membered heterocyclic silanolates
Denmark, Scott E.,Baird, John D.,Regens, Christopher S.
, p. 1440 - 1455 (2008/04/12)
(Chemical Equation Presented) The preparation of π-rich 2-aryl heterocycles by palladium-catalyzed cross-coupling of sodium heteroarylsilanolates with aryl iodides, bromides, and chlorides is described. The cross-coupling process was developed through extensive optimization of the following key variables: (1) identification of stable, isolable alkali metal silanolates, (2) identification of conditions for preformation and isolation of silanolate salts, (3) judicious choice in the palladium catalyst/ligand combination, and (4) selection of the protecting group on the nitrogen of indole. It was found that the alkali metal silanolates, either isolated or formed in situ, offered a significant rate enhancement and broader substrate scope over the use of silanols activated by Bronsted bases such as NaOt-Bu. In addition, the optimized conditions for the cross-coupling of 2-indolylsilanolates were readily applied to the cross-coupling of 2-pyrrolyl-, 2-furyl-, and 2-thienylsilanolates.