87996-94-9

Basic information

• Product Name: racemic (3S,4R)-1-(allyloxycarbonyl)methyl-3-((R)-1-t-butyldimethylsilyloxyethyl)-4-triphenylmethylthio-2-azetidinone
• CAS NO: 87996-94-9
• Molecular Weight: 601.882
• Mol File: 87996-94-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: racemic (3S,4R)-1-(allyloxycarbonyl)methyl-3-((R)-1-t-butyldimethylsilyloxyethyl)-4-triphenylmethylthio-2-azetidinone(CAS DataBase Reference)
• NIST Chemistry Reference: racemic (3S,4R)-1-(allyloxycarbonyl)methyl-3-((R)-1-t-butyldimethylsilyloxyethyl)-4-triphenylmethylthio-2-azetidinone(87996-94-9)
• EPA Substance Registry System: racemic (3S,4R)-1-(allyloxycarbonyl)methyl-3-((R)-1-t-butyldimethylsilyloxyethyl)-4-triphenylmethylthio-2-azetidinone(87996-94-9)

Safety Data

• Hazardous Substances Data: 87996-94-9(Hazardous Substances Data)

Upstream product

• 40630-84-0 allyl bromoacetate 
• 87996-93-8 racemic (3S,4R)-3-((R)-1-(t-butyldimethylsilyloxy)ethyl)-4-triphenylmethylthio-2-azetidinone 
• 75939-72-9 racemic (3S,4R)-3-((R)-1-hydroxyethyl)-4-triphenylmethylthio-2-azetidinone 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 87996-96-1 racemic (3S,4R)-1-(allyloxycarbonyl)methyl-3-<((R)-1-t-butyldimethylsilyloxy)-ethyl>-4-phenoxy(thiocarbonyl)thio-2-azetidinone 

Relevant articles and documents

AN EFFICIENT SYNTHESIS OF 2-SUBSTITUTED-THIO-6-HYDROXYETHYL-PENEM-3-CARBOXYLIC ACIDS VIA 2-THIOXOPENAMS

Allyl and p-nitrobenzyl (5R,6S)-6-((R)-1-(t-butyldimethylsilyloxy)ethyl)-2-thioxopenam-3-carboxylates (19) were synthesized by base mediated cyclization of the corresponding 1-carboxylmethyl-4-phenoxy(thiocarbonyl)thio-2-azetidinones (16).The thioxopenams underwent alkylation and Michael reactions to produce 2-alkylthio- and 2-alkenylthio-penem derivatives 20 and 21.