88-62-0

Basic information

• Product Name: 3-aminotoluene-4-sulphonic acid
• Synonyms: 3-aminotoluene-4-sulphonic acid;2-Amino-p-toluenesulfonic acid;m-Toluidine-p-sulfonic acid;2-amino-4-methyl-Benzenesulfonic acid
• CAS NO: 88-62-0
• Molecular Formula: C₇H₉NO₃S
• Molecular Weight: 187.21626
• EINECS: 201-844-4
• Mol File: 88-62-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 500°C (rough estimate)
• Flash Point: °C
• Appearance: /
• Density: 1.3553 (rough estimate)
• Refractive Index: 1.6100 (estimate)
• CAS DataBase Reference: 3-aminotoluene-4-sulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-aminotoluene-4-sulphonic acid(88-62-0)
• EPA Substance Registry System: 3-aminotoluene-4-sulphonic acid(88-62-0)

Safety Data

• Hazardous Substances Data: 88-62-0(Hazardous Substances Data)

Usage

Safety Profile

Mildly toxic by ingestion. Asevere eye irritant. When heatedto decomposition it emits very toxic fumes of NOx andSOx.

InChI:InChI=1/C7H9NO3S/c1-5-2-3-7(6(8)4-5)12(9,10)11/h2-4H,8H2,1H3,(H,9,10,11)

Upstream product

• 67-56-1 methanol 
• 4288-90-8 2-nitro-4-toluenylsulfenyl chloride 
• 88-53-9 5-amino-2-chloro-toluene-4-sulfonic acid 
• 2942-16-7 5-methylbenzo[d]thiazole 

Downstream Products

• 139778-26-0 2-iodo-4-methylbenzenesulfonic acid 

Relevant articles and documents

-

-

Development of an efficient ruthenium catalyzed synthetic process and mechanism for the facile conversion of benzothiazoles to orthanilic acids

Ruthenium-Schiff base complex catalyzed efficient protocol has been developed for the synthesis of orthanilic acids from benzothiazoles in good to excellent yields using N-haloamines. Hexa-coordinated ruthenium complex with Schiff base and triphenylphosphine ligands has been prepared and its catalytic function was invented for the synthesis of orthanilic acids. The synthetic process utilizes our efficient method for the selective and preferential oxidation of thiazole ring of benzothiazoles using N-haloamines without effecting phenyl ring. The detailed catalytic, mechanistic and kinetic investigations have been made for the synthetic reactions. Solvent isotope studies have been made in H2O-D2O and the reactions were carried out at different temperatures. Under the identical set of conditions, the kinetics of catalyzed reactions has been compared with uncatalyzed reactions and found that the catalyzed reactions are 9-11 folds faster. The catalytic constants (KC) have been calculated for each N-haloamine at different temperatures and the values of activation parameters with respect to the catalyst have been evaluated. Spectroscopic evidence for the formation of 1:1 complex between N-haloamine and ruthenium has been obtained. The observed results have been explained by a plausible mechanism and the related rate law has been deduced.