880158-60-1

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-methoxyphenyl ester
• CAS NO: 880158-60-1
• Molecular Formula: C14H18F3NO6S
• Molecular Weight: 385.361
• Mol File: 880158-60-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-methoxyphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-methoxyphenyl ester(880158-60-1)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-methoxyphenyl ester(880158-60-1)

Safety Data

• Hazardous Substances Data: 880158-60-1(Hazardous Substances Data)

Upstream product

• 943153-33-1 trifluoro-methanesulfonic acid 4-aminomethyl-2-methoxy-phenyl ester hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 40906-82-9 bis(trifluoromethylsulfonyl)phenylmethane 
• 130972-89-3 (4-hydroxy-3-methoxybenzyl)carbamic acid tert-butyl ester 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 943153-34-2 [4-(5-chloro-2-methoxy-pyridin-3-yl)-3-methoxy-benzyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Arylboronic acids as dual-action FAAH and TRPV1 ligands

A series of 31 arylboronic acids designed on the basis of the pharmacophore model for a variety of TRPV1 antagonists was prepared and tested on FAAH and TRPV1 channel. Four of them, that is, compounds 3c, 4a, 5a,b acted as dual FAAH/TRPV1 blockers with IC50 values between 0.56 and 8.11 μM whereas ten others (compounds 1c,f-i, 2c-f, 4b) inhibited FAAH and activated/desensitized TRPV1.

Compounds with medicinal effects due to interaction with the glucocorticoid receptor

The invention provides for compounds having the structure according to the formula I