88054-24-4Relevant articles and documents
Chemical deoxygenation of the epoxide moiety in deoxynivalenol (vomitoxin)
King, Russell R.,Greenhalgh, Roy
, p. 1089 - 1092 (2007/10/02)
Reaction of triacetoxydeoxynivalenol (3) with hydrobromic acid - acetic acid at reflux temperatures yielded 3α,7α,13,15-tetraacetoxy-2-bromo apotrichothec-9-en-8-one (5) and 3α,7α,15-triacetoxy-13-bromo-12-hydroxytrichothec-9-en-8-one (4).Dehalohydrination of the 13,12-bromohydrin derivative with Zn - acetic acid followed by deacetylation with sodium ethoxide gave 3α,7α,15-trihydroxytrichothec-9,12-dien-8-one (2).This compound proved identical to the transformation product isolated from incubation of deoxynivalenol (vomitoxin) in vitro with rumen microorganisms.