88057-20-9

Basic information

• Product Name: 4-[2-Hydroxy-1-(4-nitro-phenyl)-ethoxy]-butan-1-ol
• CAS NO: 88057-20-9
• Molecular Weight: 255.271
• Mol File: 88057-20-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-Hydroxy-1-(4-nitro-phenyl)-ethoxy]-butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-Hydroxy-1-(4-nitro-phenyl)-ethoxy]-butan-1-ol(88057-20-9)
• EPA Substance Registry System: 4-[2-Hydroxy-1-(4-nitro-phenyl)-ethoxy]-butan-1-ol(88057-20-9)

Safety Data

• Hazardous Substances Data: 88057-20-9(Hazardous Substances Data)

Upstream product

• 109-99-9 tetrahydrofuran 
• 6388-74-5 p-Nitrophenyloxirane 
• 19922-82-8 2-bromo-1-(4-nitrophenyl)ethanol 
• 100-19-6 (4-nitrophenyl)ethanone 
• 99-81-0 4-Nitrophenacyl bromide 

Relevant articles and documents

Antibacterial Benzisoxazolones. An Unusual Rearrangement Product from o-Nitrostyrene Oxide en Route to the Photolabile Carbonyl Protecting Group (o-Nitrophenyl)ethylene Glycol

In the process of synthesizing the known, photolabile protecting group (o-nitrophenyl)ethylene glycol, we uncovered an acid-mediated rearrangement of o-nitrostyrene oxide to 1-(hydroxymethyl)-2,1-benzisoxazol-3(1H)-one.The structure was ascertained by IR, UV, 1H NMR, 13C NMR, MS, and X-ray crystallography.Also the benzisoxazolone was prepared by independent synthesis from an o-nitrobenzoate.Another novel transformation uncovered was the conversion of o-nitrostyrene oxide to 2-(o-nitrophenyl)ethanol with use of potassium hydroxide and 18-crown-6.Similiar chemistry was insignificant with p-nitrostyrene oxide.The benzisoxazolone exhibited antibacterial and antileukemic activity (in vitro).