88059-53-4

Basic information

• Product Name: Pyridine, 4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]-
• CAS NO: 88059-53-4
• Molecular Formula: C14H11N3O
• Molecular Weight: 237.261
• Mol File: 88059-53-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 136-137 °C(Solv: acetone (67-64-1); water (7732-18-5))
• Boiling Point: 420.6±55.0 °C(Predicted)
• Density: 1.193±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Pyridine, 4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]-(88059-53-4)
• EPA Substance Registry System: Pyridine, 4-[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]-(88059-53-4)

Safety Data

• Hazardous Substances Data: 88059-53-4(Hazardous Substances Data)

Upstream product

• 1594-57-6 isonicotinamidoxime 
• 99-94-5 p-Toluic acid 
• 63824-98-6 4-Methyl-N-pyridin-4-ylmethyl-benzamide 

Relevant articles and documents

The accelerated development of an optimized synthesis of 1,2,4-oxadiazoles: Application of microwave irradiation and statistical design of experiments

Herein, we report the development of an optimized microwave-assisted synthesis of 1,2,4-oxadiazoles. The chemistry development process was significantly accelerated by employing a statistical software package (MODDE 6.0) to guide in the optimization of the reaction conditions. The resulting optimized reaction conditions were then utilized in the synthesis of a focused library of 1,2,4-oxadiazoles.