88059-54-5Relevant articles and documents
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening
Pibiri, Ivana,Lentini, Laura,Tutone, Marco,Melfi, Raffaella,Pace, Andrea,Di Leonardo, Aldo
, p. 429 - 435 (2016/07/15)
Ataluren, also known as PTC124, is a 5-(fluorophenyl)-1,2,4-oxadiazolyl-benzoic acid suggested to suppress nonsense mutations by readthrough of premature stop codons in the mRNA. Potential interaction of PTC124 with mRNA has been recently studied by molec
Synthesis of 5-aryl-3-(4-pyridyl)-1,2,4-oxadiazoles
Brana,Castellano,Yunta
, p. 1403 - 1405 (2007/10/02)
The title oxadiazoles were formed in the reaction of N-(4-pyridylmethyl)arylamides with nitrosyl chloride in low yields.