880647-72-3Relevant articles and documents
Diastereoselective fischer-type pyrroloindole synthesis and its application to the synthesis of chiral pyrroloindole alkaloids
Nishida, Atsushi,Ushigome, Satoru,Sugimoto, Ayako,Arai, Shigeru
, p. 181 - 185 (2007/10/03)
Facile access to optically active pyrroloindoles by Fischer-type pyrroloindole synthesis is investigated. The reaction using chiral hydrazines prepared from commercially available chiral amines proceeded with diastereoselective cyclization (up to 70% de), and a short-step conversion of the cycloadducts to (-)-desoxyeseroline and pyrroloindole alkaloids was achieved.