88075-88-1

Basic information

• Product Name: 1H-Pyrrole-3-carboxaldehyde, 1-(4-chlorophenyl)-
• CAS NO: 88075-88-1
• Molecular Formula: C11H8ClNO
• Molecular Weight: 205.644
• Mol File: 88075-88-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carboxaldehyde, 1-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxaldehyde, 1-(4-chlorophenyl)-(88075-88-1)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxaldehyde, 1-(4-chlorophenyl)-(88075-88-1)

Safety Data

• Hazardous Substances Data: 88075-88-1(Hazardous Substances Data)

Usage

Aromatic heterocycle

pyrrole with a nitrogen atom

Derivative of pyrrole

with a formyl group attached

Aldehyde

formyl group attached to the pyrrole ring

Substituent

4-chlorophenyl group

Position of substituent

attached to the pyrrole ring at the 1-position

Uses

in the synthesis of various pharmaceuticals and organic compounds

Chemical properties

useful in a variety of chemical reactions and processes

Upstream product

• 133748-91-1 1-(4-chlorophenyl)-3-hydroxymethylpyrrolidine 
• 226881-06-7 N-(4-chlorophenyl)-2-oxo-pyrrolidine-3-carboxylic acid 
• 106-47-8 4-chloro-aniline 
• 39629-87-3 1-(4-chlorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid 
• 97-65-4 2-methylenesuccinic acid 
• 50634-05-4 2,5-dimethoxy-3-tetrahydrofurancarboxaldehyde 

Relevant articles and documents

Optimization of non-ATP competitive CDK/cyclin groove inhibitors through REPLACE-mediated fragment assembly

A major challenge in drug discovery is to develop and improve methods for targeting protein-protein interactions. Further exemplification of the REPLACE (REplacement with Partial Ligand Alternatives through Computational Enrichment) strategy for generatin

Sodium borohydride-iodine mediated reduction of γ-lactam carboxylic acids followed by DDQ mediated oxidative aromatisation: A facile entry to N-aryl-formylpyrroles

A simple methodology for the conversion of substituted N-aryl-γ- lactam 2/3-carboxylic acids to substituted N-aryl-2/3-formyl-pyrroles has been developed. Several N-aryl-γ-lactam 2/3-carboxylic acids were reduced to substituted (N-aryl-pyrrolidine-2/3-yl)

SYNTHESIS OF 1-SUBSTITUTED PYRROLE-3-CARBOXALDEHYDES

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