880762-08-3Relevant articles and documents
Tetrabutylammonium pyridin-2-olate: A new reagent for the efficient synthesis of N-aryl pyridin-2-ones
Zhang, Huiping,Chen, Bang-Chi,Wang, Bei,Chao, Sam T.,Zhao, Rulin,Lim, Ngiapkie,Balasubramanian, Balu
experimental part, p. 1523 - 1526 (2009/04/06)
A new reagent, tetrabutylammonium pyridin-2-olate, was prepared and its application to the efficient synthesis of N-aryl pyridine-2-ones was demonstrated using CuI-catalyzed coupling reactions with aryl iodides. This coupling reaction is mild, high-yielding, and remarkably chemoselective (N- vs. O-arylation). It is also compatible with substrates containing labile functional groups. Georg Thieme Verlag Stuttgart.