88096-03-1Relevant articles and documents
S-alkylated homocysteine derivatives: New inhibitors of human betaine-homocysteine S-methyltransferase
Jiracek, Jiri,Collinsova, Michaela,Rosenberg, Ivan,Budesinsky, Milos,Protivinska, Eva,Netusilova, Hana,Garrow, Timothy A.
, p. 3982 - 3989 (2007/10/03)
A series of S-alkylated derivatives of homocysteine were synthesized and characterized as inhibitors of human recombinant betaine-homocysteine S-methyltransferase (BHMT). Some of these compounds inhibit BHMT with IC 50 values in the nanomolar r