88139-27-9

Basic information

• Product Name: 1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-4-(3-pyridylcarbonyl)methyl-azetidin-2-one
• Synonyms: 1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-4-(3-pyridylcarbonyl)methyl-azetidin-2-one
• CAS NO: 88139-27-9
• Molecular Weight: 643.635
• Mol File: 88139-27-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-4-(3-pyridylcarbonyl)methyl-azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-4-(3-pyridylcarbonyl)methyl-azetidin-2-one(88139-27-9)
• EPA Substance Registry System: 1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidene)methyl-4-(3-pyridylcarbonyl)methyl-azetidin-2-one(88139-27-9)

Safety Data

• Hazardous Substances Data: 88139-27-9(Hazardous Substances Data)

Upstream product

• 21970-14-9 pyridin-3-ylmagnesium bromide 
• 88139-24-6 1-(o-nitrobenzyloxycarbonyltriphenylphosphoranylidine)methyl-4-(2-pyridylthiocarbonyl)methyl-azetidin-2-one 
• 626-55-1 3-Bromopyridine 
• 88139-21-3 ((S)-2-Carboxymethyl-4-oxo-azetidin-1-yl)-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 
• 88139-22-4 ((S)-2-Chlorocarbonylmethyl-4-oxo-azetidin-1-yl)-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 
• 88198-11-2 [(R)-2-(2-Hydroxy-ethyl)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 

Downstream Products

• 88139-59-7 o-nitrobenzyl-2-(3-pyridyl)-1-carbapen-2-em-3-carboxylate 

Relevant articles and documents

Total synthesis of thienamycin analogs - III. Synthesis of 2-aryl and 2-heteroaryl analogs of theinamycin

The total syntheses of 2-aryl and 2-heteroaryl carbapen-2-em-3-carboxylic acids with and without a 6-hydroxyethyl side chain, using Wittig cyclization for formation of the bicyclic ring system is described. Antibacterial activity of the compounds synthesized is discussed.