88141-37-1

Basic information

• Product Name: (1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine
• Synonyms: 2-Cyclohexen-1-one, 3-phenyl-, oxime
• CAS NO: 88141-37-1
• Molecular Formula: C₁₂H₁₃NO
• Molecular Weight: 187.2377
• Mol File: 88141-37-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 348.37°C at 760 mmHg
• Flash Point: 217.225°C
• Density: 1.097g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: (1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine(88141-37-1)
• EPA Substance Registry System: (1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine(88141-37-1)

Safety Data

• Hazardous Substances Data: 88141-37-1(Hazardous Substances Data)

Usage

Description

(1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine is a cyclohexenimine derivative with the molecular formula C13H13NO. It features a hydroxy group attached to the nitrogen atom, giving it unique structural and potential biological properties. This chemical compound holds promise for pharmaceutical research and drug development, as well as for use as a reagent in organic synthesis and chemical reactions. Its properties and reactivity also make it a valuable subject for further study in organic chemistry.

Uses

Used in Pharmaceutical Research and Drug Development:
(1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine is used as a chemical compound in pharmaceutical research and drug development due to its unique structure and potential biological activity. Its specific properties may contribute to the discovery and creation of new medications.
Used as a Reagent in Organic Synthesis and Chemical Reactions:
In the field of organic chemistry, (1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine serves as a reagent, facilitating various chemical reactions and synthesis processes. Its reactivity and properties make it a useful tool for chemists working on the development of new organic compounds.
Used in Organic Chemistry Research:
(1E)-N-hydroxy-3-phenylcyclohex-2-en-1-imine is also utilized in organic chemistry research to explore its properties and reactivity. This study can lead to a better understanding of its behavior in chemical reactions and may uncover new applications or reactions involving this compound.

Upstream product

• 10345-87-6 3-phenylcyclohex-2-enone 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 504-02-9 1,3-cylohexanedione 
• 24740-28-1 ethyl 5-phenyl-2-acetyl-5-oxopentanoate 
• 859936-34-8 2-oxo-4-phenyl-cyclohex-3-enecarboxylic acid ethyl ester 
• 768-03-6 Phenyl vinyl ketone 
• 3506-36-3 3-dimethylaminopropiophenone 

Downstream Products

• 2113-54-4 N-(biphenyl-3-yl)acetamide 
• 88141-41-7 3-phenylcyclohex-2-enone O-tosyloxime 

Relevant articles and documents

Synthesis of chiral seven-membered β-substituted lactams: Via Rh-catalyzed asymmetric hydrogenation

Rh/bisphosphine-thiourea ligand (ZhaoPhos)-catalyzed asymmetric hydrogenation of seven-membered β-substituted α,β-unsaturated lactams was successfully developed to prepare various chiral seven-membered β-substituted lactams with good to excellent results (up to >99% conversion, 99% yield, and >99% ee).

Synthesis of 3-aryl-6-aminocyclohex-2-enol derivatives

6-(N-Substituted amino)-3-arylcyclohex-2-enol was designed as a new type of β-adrenergic blocker on the basis of the X-ray crystallographic data for propranolol. Eight such compounds were prepared by a six-step sequence of reactions from 3-aryl-cyclohex-2