881673-40-1

Basic information

• Product Name: 1H-Pyrrole-3-carboxaldehyde, 5-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-
• CAS NO: 881673-40-1
• Molecular Formula: C18H14FNO3S
• Molecular Weight: 343.378
• Mol File: 881673-40-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carboxaldehyde, 5-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxaldehyde, 5-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-(881673-40-1)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxaldehyde, 5-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-(881673-40-1)

Safety Data

• Hazardous Substances Data: 881673-40-1(Hazardous Substances Data)

Usage

Molecular structure

1H-Pyrrole-3-carboxaldehyde, 5-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]consists of a pyrrole ring with a carboxaldehyde group at the 3-position and a 5-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl] substituent.

Potential applications

May have potential applications in the pharmaceutical industry.

Synthesis building block

Structure suggests it could be used in the synthesis of other organic compounds or as a building block for more complex molecules.

Chemical reactivity

Presence of both a sulfonyl and a fluorophenyl group indicates unique chemical reactivity.

Biological activities

Potentially exhibit interesting biological activities due to the presence of sulfonyl and fluorophenyl groups.

Further research needed

More research and testing is necessary to fully understand the properties and potential uses of this compound.

Upstream product

• 250213-74-2 Ethyl 5-(4-fluorophenyl)-1H-pyrrole-3-carboxylate 
• 250213-69-5 Ethyl 2-chloro-5-(4-fluorophenyl)-1H-pyrrole-3-carboxylate 
• 131952-81-3 Ethyl 2-cyano-4-(4-fluorophenyl)-4-oxobutanoate 
• 403-29-2 2-bromo-4'-fluoroacetophenone 

Relevant articles and documents

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action

With the aim to find a novel long-lasting potassium-competitive acid blocker (P-CAB) that would perfectly overcome the limitations of proton pump inhibitors (PPIs), we tried various approaches based on pyrrole derivative 1b as a lead compound. As part of

PROTON PUMP INHIBITORS

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R2, R3 and R4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R5 and R6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.