881677-11-8 Usage
Description
1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)is a complex organic compound with a unique molecular structure that features a pyrrole ring, a carbaldehyde group, a 2-fluorophenyl moiety, and a 3-pyridinylsulfonyl substituent. 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)is characterized by its potential reactivity and versatility in chemical synthesis and medicinal chemistry applications.
Uses
Used in Pharmaceutical Industry:
1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)is used as an intermediate in the synthesis of various pharmaceutical compounds for the treatment of acid-related diseases. Its unique structure allows for the development of novel drugs with improved efficacy and reduced side effects.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)serves as a valuable building block for the design and synthesis of new drug candidates. Its presence in the molecular structure can impart specific biological activities, making it a promising candidate for the development of targeted therapies.
Used in Impurity Profiling:
As an impurity of Vonaprazan (V767010), a novel potassium-competitive acid blocker, 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)is important for impurity profiling and quality control in the pharmaceutical industry. Understanding and controlling the presence of this impurity ensures the safety and efficacy of the final drug product.
Check Digit Verification of cas no
The CAS Registry Mumber 881677-11-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,6,7 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 881677-11:
(8*8)+(7*8)+(6*1)+(5*6)+(4*7)+(3*7)+(2*1)+(1*1)=208
208 % 10 = 8
So 881677-11-8 is a valid CAS Registry Number.
881677-11-8Relevant articles and documents
Identification, characterization, synthesis of major metabolites biotransformed from vonoprazan fumarate
Hu, Ji'an,Kou, Jingping,Li, Jianbing,Li, Yanhua,Lin, Biyue,Wang, Zhongqing,Wu, Shuming,Xiao, Qingbo,Xin, Libo,Zhou, Xinglin,Zhu, Zhu
, (2022/02/10)
A first synthetic research concerning four observed metabolites and their deuterium-labeled analogues of reflux esophagitis drug vonoprazan fumarate is reported. Among which the synthetic methods of three metabolites M ? I, M-III, M-IV-Sul, and four stable isotop labeled analogues M-I-d4, M-II-d4, M-III-d4, M-IV-Sul-d4 have not yet been reported before. The structures of these compounds were elucidated on the basis of MS and NMR spectroscopy.
Preparation method of tenosynol fumarate
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Paragraph 0024-0032, (2021/11/19)
The invention discloses a preparation method of fumarate administered by a synthetic digestive system. In particular, the invention relates to a method for large-scale preparation of tenoteno fumarate; the adopted starting materials are easy to obtain; th
3-pyridinesulfonyl-1-N-heteropyrrole derivatives capable of treating peptic ulcer as well as preparation method and application thereof
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Paragraph 0104-0108, (2020/11/26)
The invention discloses 3-pyridinesulfonyl-1-N-heteropyrrole derivatives capable of treating peptic ulcer as well as a preparation method and application of the derivative, and particularly provides compounds as shown in a formula I, or pharmaceutically a
