88203-16-1Relevant articles and documents
Sonogashira cross-coupling reaction in 4-chloro-2- trichloromethylquinazoline series is possible despite a side dimerization reaction
Kieffer, Charline,Verhaeghe, Pierre,Primas, Nicolas,Castera-Ducros, Caroline,Gellis, Armand,Rosas, Roselyne,Rault, Sylvain,Rathelot, Pascal,Vanelle, Patrice
, p. 2987 - 2995 (2013/03/29)
We studied the Sonogashira coupling reaction between 4-chloro-2- trichloromethylquinazoline and various terminal alkynes, mainly in phenylacetylene series. A brief review of the literature shows that mono- or polybromo/chloromethylated substrates, especia
REACTION OF NITRILES UNDER ACIDIC CONDITIONS: A NOVEL, DIRECT FORMATION OF CONDENSED 4-CHLOROPYRIMIDINES
Shishoo, C. J.,Devani, M. B.,Bhadti, V. S.,Anathan, S.,Ullas, G. V.
, p. 4611 - 4612 (2007/10/02)
An unusual formation of condensed 4-chloropyrimidines in the reaction of o-aminonitriles with halogenoacetonitriles in the presence of dry hydrogen chloride gas is described.