882033-76-3Relevant articles and documents
Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists
Di Fabio, Romano,Giovannini, Riccardo,Bertani, Barbara,Borriello, Manuela,Bozzoli, Andrea,Donati, Daniele,Falchi, Alessandro,Ghirlanda, Damiano,Leslie, Colin P.,Pecunioso, Angelo,Rumboldt, Giovanna,Spada, Simone
, p. 1749 - 1752 (2006)
The SAR of a new series of tetrahydrocarbazole derivatives is described: the appropriate decoration of this template led to the identification of a new class of NPY-1 antagonists showing good in vitro potency and a promising in vivo pharmacokinetic profil