88218-84-2Relevant articles and documents
From 1,2-difunctionalisation to cyanide-transfer cascades-Pd-catalysed cyanosulfenylation of internal (oligo)alkynes
Bürger, Marcel,Loch, Maximilian N.,Jones, Peter G.,Werz, Daniel B.
, p. 1912 - 1917 (2020)
Internal alkynes substituted by aliphatic or aromatic moieties or by heteroatoms were converted into sulphur-substituted acrylonitrile derivatives. Key is the use of Pd catalysis, which allows the addition of aromatic and aliphatic thiocyanates in an intra- A nd intermolecular manner. Substrates with several alkyne units underwent further carbopalladation steps after the initial thiopalladation step, thus generating in a cascade-like fashion an oligoene unit with sulphur at one terminus and the cyano group at the other.
