882875-01-6Relevant articles and documents
Optimization and biological evaluation of aminopyrimidine-based IκB kinase β inhibitors with potent anti-inflammatory effects
Shin, Yongje,Lim, Sang Min,Yan, Hong Hua,Jung, Sungwoo,Fang, Zhenghuan,Jung, Kyung Hee,Hong, Soon-Sun,Hong, Sungwoo
, p. 544 - 556 (2016/08/12)
Targeting IκB kinase β (IKKβ) can be a promising strategy in the development of a therapeutic treatment of inflammatory diseases because IKKβ is well-recognized as a key mediator of the NF-κB signaling pathway. In this study, we have successfully develope
Anilino-pyrimidine phenyl and benzothiophene analogs
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Page/Page column 17, (2008/06/13)
The present invention relates to compounds of formula III: wherein R2, R3, R5 and R6 are as defined herein.