88336-80-5

Basic information

• Product Name: Benzenedodecanol
• CAS NO: 88336-80-5
• Molecular Formula: C18H30O
• Molecular Weight: 262.436
• Mol File: 88336-80-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenedodecanol(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenedodecanol(88336-80-5)
• EPA Substance Registry System: Benzenedodecanol(88336-80-5)

Safety Data

• Hazardous Substances Data: 88336-80-5(Hazardous Substances Data)

Upstream product

• 51795-88-1 1-bromo-10-(tetrahydropyranyloxy)decane 
• 536-74-3 phenylacetylene 
• 100-52-7 benzaldehyde 
• 68532-63-8 (11-methoxy-11-oxoundecyl)(triphenyl)phosphonium bromide 
• 112999-97-0 2-[(12-bromododecyl)oxy]tetrahydro-2H-pyran 
• 87305-70-2 11-bromo-1-phenyl-1-undecanone 
• 57691-19-7 11-cyano-1-phenylundecan-1-one 
• 14507-27-8 12-Phenyldodecanoic Acid 
• 15949-84-5 11-bromoundecanoyl chloride 
• 2834-05-1 11-bromoundecanoic acid 
• 106484-81-5 1-Phenyl-12-(tetrahydro-pyran-2-yloxy)-dodecan-1-ol 
• 106484-80-4 12-(tetrahydropyran-2'-yloxy)dodecanal 
• 111456-75-8 12-(tetrahydropyran-2'-yloxy)dodecan-1-ol 
• 5675-51-4 1,12-dodecandiol 

Downstream Products

• 85070-63-9 1-bromo-12-phenyl-dodecane 
• 106484-83-7 phenyl-laurylaldehyde 
• 88337-01-3 14-(p-iodophenyl)tetradecanoic acid 
• 88336-96-3 1-(4,4-dimethyl-2-oxazolin-2-yl)-13-phenyltridecane 
• 88336-83-8 ethyl 14-phenyl-2(RS)-methyltetradecanoate 
• 88336-94-1 14-(p-iodophenyl)-2(RS)-methyltetradecanoic acid 
• 88336-82-7 2(RS)-(4,4-dimethyl-2-oxazolin-2-yl)-14-phenyltetradecane 
• 88336-98-5 ethyl 14-(p-iodophenyl)tetradecanoate 
• 88336-93-0 methyl 15-(p-iodophenyl)-3(RS)-methylpentadecanoate 
• 88336-92-9 ethyl 14-(p-iodophenyl)-2(RS)-methyltetradecanoate 
• 102947-50-2 2,14-diphenyl-tetradecanoic acid 
• 105419-06-5 3-(12'-phenyldodecyl)veratrole 
• 105419-04-3 O-dimethyl-4-(12'-phenyldodecyl)catechol 
• 95690-69-0 4-(12'-phenyldodecyl)benzene-1,2-diol 

Relevant articles and documents

NUCLEOSIDE PRODRUGS AND USES RELATED THERETO

Disclosed are acyclic nucleoside prodrugs with improved metabolic stability and oral bioavailability. In general, the prodrugs are derivatives of acyclic nucleoside phosphonates containing a lipid-like moiety that can increase oral absorption and subsequent stability in the liver and plasma. Preferably, the lipid-like moiety can resist enzyme-mediated ω-oxidation, such as ω -oxidation catalyzed by cytochrome P450 enzymes. Also disclosed are pharmaceutical formulations of the acyclic nucleoside prodrugs. The acyclic nucleoside prodrugs and pharmaceutical formulations thereof can be used to treat viral infections, such as HIV infections, and/or viral-associated cancer, such as HPV-associated cancers.

Selective antiproliferative activity of caffeic acid phenethyl ester analogues on highly liver-Metastatic murine colon 26-L5 carcinoma cell line

Caffeic acid phenethyl ester (CAPE, 2) and its 20 analogues (1, 3-21) were prepared. These esters were tested by MTT assay on growth of murine colon 26-L5 carcinoma, murine B16-BL6 malonoma, murine Lewis lung carcinoma, human HT-1080 fibrosarcoma, human lung A549 adenocarcinoma, and human cervix HeLa adenocarcinoma cell lines. It was found that CAPE analogues possessed selective antiproliferative activity toward highly liver-metastatic murine colon 26-L5 carcinoma cell line. Among them, 4-phenylbutyl caffeate (4), (Z)-8-phenyl-7-octenyl (10a) and (E)-8-phenyl-7-octenyl (10b) caffeate showed the most potent antiproliferative activity (EC50 value, 0.02μM). In addition, CAPE (2) induced DNA fragmentation at concentrations of 1 to 10μg/mL towards murine colon 26-L5 carcinoma cells. Copyright

Synthesis of 3-(ω-Phenylalkyl)catechols, Phenolic Lipids found in Sap of the Burmese Lac Tree, via Directed Metallation

3-(ω-Phenylalkyl)catechols were synthesized via directed metallation.