88347-91-5

Basic information

• Product Name: Cysteine, N-acetyl-S-phenyl-, methyl ester
• CAS NO: 88347-91-5
• Molecular Formula: C12H15NO3S
• Molecular Weight: 253.322
• Mol File: 88347-91-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Cysteine, N-acetyl-S-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cysteine, N-acetyl-S-phenyl-, methyl ester(88347-91-5)
• EPA Substance Registry System: Cysteine, N-acetyl-S-phenyl-, methyl ester(88347-91-5)

Safety Data

• Hazardous Substances Data: 88347-91-5(Hazardous Substances Data)

Upstream product

• 7652-46-2 2-acetylamino-3-mercapto-propionic acid methyl ester 
• 98-80-6 phenylboronic acid 
• 32381-28-5 N,N'-diacetylcystine dimethyl ester 
• 882-33-7 diphenyldisulfane 
• 35356-70-8 Methyl 2-acetamidoacrylate 
• 108-98-5 thiophenol 
• 5429-56-1 N-Acetamidoacrylic acid 
• 591-50-4 iodobenzene 
• 186581-53-3 diazomethane 
• 20640-68-0 2-acetylamino-3(phenylthio)propionic acid 

Downstream Products

• 89024-26-0 2-acetylamino-N-methyl-3(phenylthio)propionamide 

Relevant articles and documents

Dealkenylative Thiylation of C(sp3)-C(sp2) Bonds

Carbon-carbon bond fragmentations are useful methods for the functionalization of molecules. The value of such cleavage events is maximized when paired with subsequent bond formation. Herein we report a protocol for the cleavage of an alkene C(sp3)-C(sp2) bond, followed by the formation of a new C(sp3)-S bond. This reaction is performed in nonanhydrous solvent and open to the air, employs common starting materials, and can be used to rapidly diversify natural products.

Methyl mercapturate synthesis: An efficient, convenient and simple method

A safe and simple method for methyl S-arylmercapturate synthesis is described. Thirteen such compounds, to be used afterwards in metabolism studies, have been obtained with yields ranging from 71 to 99.6%. These compounds were obtained using a sulfa-Michael addition and synthesized by adding the corresponding thiophenols to a mixture composed of methyl 2-acetamidoacrylate (MAA), potassium carbonate and a phase transfer catalyst, Aliquat 336. MAA, the initial synthon, was itself isolated in quasi quantitative yield following a fully described synthesis.

S-substituted 2-azido-3-mercapto-propionic acid ester and process for its production and use

The subject matter of the invention are S-substituted 2-azido-3-mercapto-propionic acid esters of the general formula STR1 in which R1 is a methyl or ethyl group and R2 is an unsubstituted or substituted alkyl group, a cycloalkyl group, an unsubstituted or substituted aromatic or heteroaromatic group or a benzyl group, and a process for their production by reaction of a methyl or ethyl ester of 2-chloroacrylic acid with a corresponding thiol to form an S-substituted 2-chloro-3-mercapto-propionic acid ester and subsequently exchanging the chlorine atom with an azido group as well as use of the compounds of formula (I) as intermediate products in the production of D,L-cysteine or derivatives of D,L-cysteine.