883874-55-3Relevant articles and documents
Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands
Jean, Micka?l,Renault, Jacques,Levoin, Nicolas,Danvy, Denis,Calmels, Thierry,Berrebi-Bertrand, Isabelle,Robert, Philippe,Schwartz,Lecomte,Uriac, Philippe,Capet, Marc
scheme or table, p. 5376 - 5379 (2010/12/24)
Isosteric replacement of the amide function and modulation of the arylpiperazine moiety of known dopamine D3 receptor ligands led to potent and selective compounds. Enhanced bioavailability and preferential brain distribution make compound 6c a good candi
3,4-dihydro-2-naphthamide derivatives as selective dopamine D3 ligands
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Page/Page column 11, (2008/06/13)
The invention relates to 3,4-dihydro-2-naphthamide derivatives of formula (I), pharmaceutical compositions containing them and their therapeutic applications as partial agonists or antagonists of the dopamine D3 receptor for the treatment of neuropsychological disorders.