884-09-3

Basic information

• Product Name: S-phenyl benzenecarbothioate
• Synonyms: benzenecarbothioic acid, S-phenyl ester
• CAS NO: 884-09-3
• Molecular Formula: C₁₃H₁₀OS
• Molecular Weight: 214.2829
• Mol File: 884-09-3.mol
• Article Data: 162

Chemical Properties

• Boiling Point: 316.7°C at 760 mmHg
• Flash Point: 135.1°C
• Density: 1.2g/cm³
• Vapor Pressure: 0.000403mmHg at 25°C
• Refractive Index: 1.64
• CAS DataBase Reference: S-phenyl benzenecarbothioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-phenyl benzenecarbothioate(884-09-3)
• EPA Substance Registry System: S-phenyl benzenecarbothioate(884-09-3)

Safety Data

• Hazardous Substances Data: 884-09-3(Hazardous Substances Data)

Upstream product

• 98-91-9 thiobenzoic acid 
• 5285-87-0 phenyl thiocyanate 
• 98-91-9 thiobenzoic acid 
• 4494-63-7 phenyl-(phenylthio)--methane 
• 98-88-4 benzoyl chloride 
• 108-98-5 thiophenol 
• 611-74-5 N,N-dimethylbenzamide 
• 4551-15-9 phenylthiotrimethylsilane 
• 93-89-0 benzoic acid ethyl ester 
• 201230-82-2 carbon monoxide 
• 139-66-2 diphenyl sulfide 
• 22946-73-2 thiophosphorous acid S-phenyl ester O,O'-dipropyl ester 
• 2397-26-4 N,N-dimethyl(chlorophenylmethylene)ammonium chloride 
• 65-85-0 benzoic acid 

Downstream Products

• 93-98-1 N-phenyl benzoyl amide 
• 24469-13-4 1-(phenylthio)-2-methyl-1-phenyl-1-propene 
• 59919-11-8 2-methyl-1-phenyl-2-(phenylthio)propan-1-one 
• 949-00-8 phenyl dithiobenzoate 
• 39504-13-7 3-hydroxy-3-(phenylthio)propyl methyl ether 
• 123295-64-7 2-benzoyloxy-3-(phenylthio)propyl methyl ether 
• 39504-39-7 1-butoxy-3-phenylthiopropan-2-ol 
• 125453-82-9 1-butoxy-3-phenylthio-2-propyl benzoate 
• 93-58-3 benzoic acid methyl ester 
• 100-52-7 benzaldehyde 
• 108-98-5 thiophenol 
• 65-85-0 benzoic acid 
• 882-33-7 diphenyldisulfane 
• 1009-14-9 phenyl butyl ketone 

Relevant articles and documents

Palladium-Catalyzed Thiocarbonylations with Triisopropylsilyl Thioethers

We have developed a palladium-catalyzed thiocarbonylation through the reaction of a σ-alkyl palladium intermediate with carbon monoxide and a triisopropylsilyl (TIPS) thioether. The use of CsF, (IPr)Pd(allyl)Cl [IPr =1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene], CO, and a TIPS thioether in THF are key to obtaining alkyl and aryl thioesters in high yields. The yield of the palladium-catalyzed thiocarbonylation depended on the structure of the substrate; indoline-2-one derivatives were formed faster than indoline derivatives. The reactions of benzoyl and hydrocinnamoyl fluorides with TIPSSPh and CsF also gave the corresponding thioesters.

Rh(I)-Catalyzed Intramolecular Decarbonylation of Thioesters

Decarbonylative synthesis of thioethers from thioesters proceeds in the presence of a catalytic amount of [Rh(cod)Cl]2 (2 mol %). The protocol represents the first Rh-catalyzed decarbonylative thioetherification of thioesters to yield valuable thioethers. Notable features include the absence of phosphine ligands, inorganic bases, and other additives and excellent group tolerance to aryl chlorides and bromides that are problematic using other metals to promote decarbonylation. Gram scale synthesis, late-stage pharmaceutical derivatization, and orthogonal site-selective cross-couplings by C-S/C-Br cleavage are reported.

Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same

Disclosed herein are embodiments of a donor compound that releases H2S by reacting with a reactive compound. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. The donor compound embodiments also can facilitate bioconjugation. Methods of making and using the donor compound embodiments also are disclosed.