88404-25-5 Usage
Description
4-Bromomethyl-6,7-dimethoxycoumarin is an organic compound that serves as a versatile fluorescent labeling and derivatization reagent in various analytical techniques. It is characterized by its ability to enhance the detection and separation of specific molecules, particularly carboxylic acids, in chromatographic and mass spectrometry methods.
Uses
Used in Analytical Chemistry:
4-Bromomethyl-6,7-dimethoaxycoumarin is used as a fluorescent labeling reagent for the reversed-phase High-Performance Liquid Chromatography (HPLC) separation and detection of carboxylic acids. Its fluorescent properties allow for improved sensitivity and selectivity in the analysis of these compounds.
Used in Pharmaceutical Analysis:
In the pharmaceutical industry, 4-Bromomethyl-6,7-dimethoxycoumarin is used as a derivatization reagent for the quantitation of specific drugs, such as clofibric, bezafibric, and fenofibric acids, in liver samples by liquid chromatography. This helps in assessing the presence and concentration of these drugs in biological systems.
Used in Biochemical Research:
4-Bromomethyl-6,7-dimethoxycoumarin is also utilized in the determination of the concentration of the tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). This application aids researchers in studying the role and distribution of glutathione in biological processes.
Used in Chromatographic Detection:
Furthermore, 4-Bromomethyl-6,7-dimethoxycoumarin is employed for the determination of carboxylic acids in chromatographic detection. Its derivatization capabilities enhance the detection and analysis of these important organic compounds in various samples.
Check Digit Verification of cas no
The CAS Registry Mumber 88404-25-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,4,0 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 88404-25:
(7*8)+(6*8)+(5*4)+(4*0)+(3*4)+(2*2)+(1*5)=145
145 % 10 = 5
So 88404-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H11BrO4/c1-15-10-4-8-7(6-13)3-12(14)17-9(8)5-11(10)16-2/h3-5H,6H2,1-2H3
88404-25-5Relevant articles and documents
Scavenger assisted combinatorial process for preparing libraries of tertiary amine compounds
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, (2008/06/13)
This invention relates to a novel solution phase process for the preparation of tertiary amine combinatorial libraries. These libraries have utility for drug discovery and are used to form wellplate components of novel assay kits.
