88418-69-3 Usage
Description
4-ISOCYANATO-TEMPO, also known as 4-isocyanato-2,2,6,6-tetramethylpiperidine-1-oxyl, is a stable nitroxide radical compound that is widely used in various applications due to its unique properties. It possesses a reactive isocyanato group that allows for covalent attachment to other molecules, and its EPR (electron paramagnetic resonance) detectable nature makes it a valuable tool in the study of biomolecules and their interactions.
Uses
Used in Biochemistry Research:
4-ISOCYANATO-TEMPO is used as a labeling agent for RNA, enabling researchers to track and analyze the structure, dynamics, and interactions of RNA molecules using EPR spectroscopy. This technique provides valuable insights into the function and behavior of RNA in various biological processes.
Used in Analytical Chemistry:
In the field of analytical chemistry, 4-ISOCYANATO-TEMPO is employed as a derivatizing agent for the detection and quantification of various analytes. Its ability to form stable covalent bonds with target molecules allows for the sensitive and selective analysis of compounds in complex samples.
Used in Material Science:
4-ISOCYANATO-TEMPO is also utilized in material science for the development of advanced materials with unique properties. Its incorporation into polymers and other materials can result in improved stability, self-healing capabilities, and enhanced performance in various applications.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-ISOCYANATO-TEMPO is employed as a tool for the design and synthesis of new drug candidates. Its ability to form stable radicals can be harnessed to develop novel therapeutic agents with improved pharmacokinetic and pharmacodynamic properties.
Overall, 4-ISOCYANATO-TEMPO is a versatile compound with a wide range of applications across various scientific disciplines, making it an important asset in the advancement of research and development efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 88418-69-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,4,1 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 88418-69:
(7*8)+(6*8)+(5*4)+(4*1)+(3*8)+(2*6)+(1*9)=173
173 % 10 = 3
So 88418-69-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H17N2O2/c1-9(2)5-8(11-7-13)6-10(3,4)12(9)14/h8H,5-6H2,1-4H3/q-1
88418-69-3Relevant articles and documents
4-Isocyano-2,2,6,6-tetramethylpiperidin-1-oxyl: A valuable precursor for the synthesis of new nitroxides
Zakrzewski, Jerzy,Jezierska, Julia,Hupko, Jaroslaw
, p. 695 - 697 (2004)
To enrich the limited set of isonitriles typically employed, 4-isocyano-2,2,6,6-teramethylpiperidin-1-oxyl (1) is proposed as an isonitrile bearing a nitroxyl moiety, Isocyanide 1 was used in some reactions characteristic of isonitriles. Isoselenocyanate, amides (products of Passerini and Ugi reactions), and tetrazole derivative were obtained. The EPR spectra of the urea derivative 5b and a product of an Ugi reaction 7 (both dinitroxides) were analyzed.
Reactions of nitroxides with sulfur-containing compounds, part IV: Synthesis of novel nitroxide (thio)ureas
Zakrzewski, Jerzy,Krawczyk, Maria
, p. 393 - 401 (2007/10/03)
The reactions of 4-isothiocyanato-2,2, 6,6-tetramethylpiperidine-1-oxyl 2 and 4-isocyanato-2,2,6,6-tetramethylpiperidine-1-oxyl 3 with selected amines and lower alcohols give the corresponding novel thioureas 4, ureas 5, thiocarbamates 6, and carbamates 7, all bearing the nitroxyl moiety. The characteristic features of EI mass spectra of (thio)ureas 4 and 5 are described. Some of the synthesized thioureas 4, ureas 5, thiocarbamates 6, and carbamates 7 are moderately or weakly active against pathogenic fungi.
SYNTHESIS OF ISOCYANATO- AND CARBODIIMIDOPIPERIDINOXYLS FRON 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-OXYL
Sen', V. D.,Kapustina, E. V.,Golubev, V. A.
, p. 1906 - 1910 (2007/10/02)
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