88422-19-9

Basic information

• Product Name: (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE&
• Synonyms: (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE&;(S)-(-)-1-(nitrophenyl)-2-pyrrolidinemethanol;)-1-(4-Nitrophenyl)-2-pyrrolidinemethanol;[(2S)-1-(4-nitrophenyl)-2-pyrrolidinyl]methanol
• CAS NO: 88422-19-9
• Molecular Formula: C₁₁H₁₄N₂O₃
• Molecular Weight: 222.2458
• Product Categories: NLO Chromophores and Intermediates;Non-Linear Optical (NLO) Materials;Photonic and Optical Materials
• Mol File: 88422-19-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 115-116 °C(lit.)
• Boiling Point: 417.878°C at 760 mmHg
• Flash Point: 206.525°C
• Appearance: /
• Density: 1.274g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE&(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE&(88422-19-9)
• EPA Substance Registry System: (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE&(88422-19-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 88422-19-9(Hazardous Substances Data)

Usage

General Description

(S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE is a chemical compound with the molecular formula C11H13N3O2. It is a pyrrolidine derivative that contains a nitrophenyl group. (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE& is used in organic chemistry and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It is also used as a chiral auxiliary in asymmetric synthesis and as a ligand for asymmetric catalysis. The (S)-(-) enantiomer of 1-(4-NITROPHENYL)-2-PYRROLIDINE has specific stereochemical properties that make it valuable in the production of enantiomerically pure compounds.

InChI:InChI=1/C11H14N2O3/c14-8-11-2-1-7-12(11)9-3-5-10(6-4-9)13(15)16/h3-6,11,14H,1-2,7-8H2/t11-/m0/s1

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 586-78-7 para-nitrophenyl bromide 
• 66158-68-7 (S)-1-(2-(hydroxymethyl) pyrrolidin-1-yl)ethanone 
• 509151-88-6 1-[(S)-2-(4-Nitro-phenoxymethyl)-pyrrolidin-1-yl]-ethanone 

Downstream Products

• 132041-37-3 [(S)-1-(4-Amino-phenyl)-pyrrolidin-2-yl]-methanol 

Relevant articles and documents

Chirality and hydrogen bonding in molecular crystals for phase-matched second-harmonic generation: N-(4-nitrophenyl)-(L)-prolinol (NPP)

The higher second-harmonic efficiency, in powder, of a new organic molecular crystal N (4-nitrophenyl)-(L)-prolinol (NPP) is reported.Electronic polarizability of NPP molecules relates to that of other para-nitroaniline-like structures such as that of pre

Synthesis and second-order nonlinearities of chiral prolinol-substituted chromophores

A new series of thiophene- and furan-containing chromophores with a chiral prolinol donor and a sulfone acceptor has been synthesized. The UV-vis absorptions, second-order nonlinear optical properties, and X-ray crystal structures are described.

Observation of O→N type smiles rearrangement in certain alkyl aryl nitro compounds

Smiles rearrangements on some alkyl aryl nitro compounds having NH2 group as the nucleophile and oxygen as the leaving group are reported.