884330-05-6

Basic information

• Product Name: 4'-(1,4'-dimethyl-2'-propyl-1H-[2,5']dibenzimidazolyl-3'-ylmethyl)biphenyl-2-carboxylic acid methyl ester hydrochloride
• Synonyms: 4'-(1,4'-dimethyl-2'-propyl-1H-[2,5']dibenzimidazolyl-3'-ylmethyl)biphenyl-2-carboxylic acid methyl ester hydrochloride
• CAS NO: 884330-05-6
• Molecular Weight: 565.115
• Mol File: 884330-05-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4'-(1,4'-dimethyl-2'-propyl-1H-[2,5']dibenzimidazolyl-3'-ylmethyl)biphenyl-2-carboxylic acid methyl ester hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-(1,4'-dimethyl-2'-propyl-1H-[2,5']dibenzimidazolyl-3'-ylmethyl)biphenyl-2-carboxylic acid methyl ester hydrochloride(884330-05-6)
• EPA Substance Registry System: 4'-(1,4'-dimethyl-2'-propyl-1H-[2,5']dibenzimidazolyl-3'-ylmethyl)biphenyl-2-carboxylic acid methyl ester hydrochloride(884330-05-6)

Safety Data

• Hazardous Substances Data: 884330-05-6(Hazardous Substances Data)

Upstream product

• 528560-93-2 4'-[[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]methyl]biphenyl-2-carboxylic acid methyl ester 
• 152628-02-9 2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole 
• 114772-38-2 Methyl 4'-(bromomethyl)biphenyl-2-carboxylate 
• 114772-34-8 methyl 4'-methylbiphenyl-2-carboxylate 

Downstream Products

• 144701-48-4 telmisatran 
• 862286-64-4 4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt 

Relevant articles and documents

An efficient and impurity-free process for telmisartan: An antihypertensive drug

Telmisartan (1), a substituted dibenzimidazole derivative, is an antihypertensive drug, essentially used to control blood pressure. An improved, cost-effective, and impurity-free process for telmisartan (1) suitable for large-scale production is described here by addressing various process development issues. The overall yield obtained from this newly developed process is around 50% (over five steps) compared to the literature reported process (21%, over eight steps).