884536-72-5

Basic information

• Product Name: (RR,RS)-5-cyano-2-(6',6'-dimethylbicyclo[3.1.1]hept-2'-en-2'-yl)-6-phenylamino-2,3-dihydro-1,3-thiazin-4(1H)-one
• CAS NO: 884536-72-5
• Molecular Weight: 351.472
• Mol File: 884536-72-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (RR,RS)-5-cyano-2-(6',6'-dimethylbicyclo[3.1.1]hept-2'-en-2'-yl)-6-phenylamino-2,3-dihydro-1,3-thiazin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (RR,RS)-5-cyano-2-(6',6'-dimethylbicyclo[3.1.1]hept-2'-en-2'-yl)-6-phenylamino-2,3-dihydro-1,3-thiazin-4(1H)-one(884536-72-5)
• EPA Substance Registry System: (RR,RS)-5-cyano-2-(6',6'-dimethylbicyclo[3.1.1]hept-2'-en-2'-yl)-6-phenylamino-2,3-dihydro-1,3-thiazin-4(1H)-one(884536-72-5)

Safety Data

• Hazardous Substances Data: 884536-72-5(Hazardous Substances Data)

Upstream product

• 103-72-0 phenyl isothiocyanate 

Relevant articles and documents

Synthesis of 2,3-dihydro-1,3-thiazin-4(1 H)-ones and their remarkably facile recyclization to 2,3-dihydropyrimidin-4(1 H)-ones

Functionalized 2,3-dihydro-1,3-thiazin-4(1 H)-one derivatives have been synthesized by cyclocondensation of 3-alkyl(aryl)amino-2-cyano-3- mercaptoacrylamides with aldehydes and ketones under acidic catalysis. 6-Alkyl(aryl)amino-5-cyano-2,3-dihydro-1,3-thiazin-4(1 H)-ones, when treated with a dilute solution of potassium hydroxide, are converted into the potassium salts of isomeric compounds, 1-alkyl-(aryl)-5-cyano-6-mercapto-2,3- dihydropyrimidin-4(1 H)-ones. Alkylation of the latter with dimethyl sulfate in situ furnishes 1-alkyl(aryl)-6-alkylthio-5-cyano-2,3-dihydropyrimidin-4(1 H)-ones, whereas boiling them in ethanol with an excess of hydrochloric acid leads to starting 2,3-dihydro-1,3-thiazin-4(1 H)-ones.