88491-44-5 Usage
Description
2-BROMO-4-HYDROXYPHENYLACETIC ACID is a chemical compound with the molecular formula C8H7BrO3. It is a derivative of phenylacetic acid with a bromo and hydroxy group attached to the phenyl ring. This versatile chemical is commonly used as a building block in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
2-BROMO-4-HYDROXYPHENYLACETIC ACID is used as a building block for the development of new pharmaceutical compounds. Its unique structure allows for the creation of various biologically active molecules, making it a valuable asset in drug discovery and development.
Used in Organic Synthesis:
In the field of organic synthesis, 2-BROMO-4-HYDROXYPHENYLACETIC ACID is used as a key intermediate for the synthesis of complex organic molecules. Its presence in the molecular structure facilitates the formation of desired products through various chemical reactions.
Used in Antifungal and Antibacterial Applications:
2-BROMO-4-HYDROXYPHENYLACETIC ACID has been studied for its potential antifungal and antibacterial properties. It is used as an active ingredient in the development of new antimicrobial agents to combat resistant strains of bacteria and fungi.
Used in Treatment of Inflammatory and Neurodegenerative Diseases:
Due to its potential therapeutic effects, 2-BROMO-4-HYDROXYPHENYLACETIC ACID is being investigated for its use in the treatment of inflammatory and neurodegenerative diseases. Its ability to modulate immune responses and protect neurons makes it a promising candidate for further research and development.
Used as a Precursor in Synthesis of Biologically Active Compounds:
2-BROMO-4-HYDROXYPHENYLACETIC ACID is also used as a precursor in the synthesis of various biologically active compounds. Its presence in the molecular structure allows for the creation of new compounds with potential applications in medicine and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 88491-44-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,4,9 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 88491-44:
(7*8)+(6*8)+(5*4)+(4*9)+(3*1)+(2*4)+(1*4)=175
175 % 10 = 5
So 88491-44-5 is a valid CAS Registry Number.
88491-44-5Relevant articles and documents
Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from 2′-hydroxyl-3-arylcoumarins
Song, Xianheng,Luo, Xiang,Sheng, Jianfei,Li, Jianheng,Zhu, Zefeng,Du, Zhibo,Miao, Hui,Yan, Meng,Li, Mingkang,Zou, Yong
, p. 17391 - 17398 (2019/06/24)
A copper-catalyzed intramolecular cross dehydrogenative C-O coupling reaction of 2′-hydroxyl-3-arylcoumarins was developed. This protocol provided a facile and efficient strategy for the construction of natural coumestans and derivatives in moderate to high yields. This transformation exhibited good functional group compatibility and was amenable to substrates with free phenolic hydroxyl groups.
Synthesis of coumestrol and aureol
Sheng, Jianfei,Xu, Tianlong,Zhang, Ensheng,Zhang, Xuejing,Wei, Wentao,Zou, Yong
, p. 2749 - 2753 (2016/11/09)
A total synthesis of coumestrol (1) and aureol (2) is described. The Perkin condensation of 2-bromo-4-hydroxylphenylacetic acid (6) and o-hydroxybenzaldehydes (7) gave the corresponding 2′-bromo-3-arylcoumarins (9). A copper-catalyzed consecutive hydroxylation and aerobic oxidative coupling of 9 under microwave conditions facilitated the total synthesis of 1 and 2, respectively, with spectroscopic data highly similar to those of natural products.
